Convenient everyday support with products recommended by health care professionals. Minor and reversible adverse effects reported in clinical trials and surveillance include GI reactions, pruritus, rash, headache, fatigue, acne, and menstrual disturbances.Roemheld-Hamm 2005, Daniele 2005, Information is limited. The most common variety of vitex used medicinally is chaste tree, which produces chasteberry (Vitex agnus-catus), a small brown berry fruit about the size of peppercorn. They are also devoid of animal-based ingredients such as dairy, eggs, honey, beeswax, and lanolin. Generally regarded as safe; mild and reversible adverse effects include GI reactions, itching, rash, headache, fatigue, acne, and menstrual disturbances. Additionally, estrogen receptor binding by phytoestrogens or linoleic acid from the fruits has been postulated as a possible mechanism for effect.Carmichael 2008, Roemheld-Hamm 2005, Tamagno 2009, A limited number of controlled clinical trials have been conducted, and reviews of these trials are concordant in finding a benefit for treatment with V. agnus-castus. Reduce Epileptic Seizures. Chaste tree is claimed to help treat painful breasts (mastodynia). Chaste Tree contains flavonoids (especially methoxylated flavones), iridoid glycosides (such as aucubin), diterpenes, sesquiterpenes, an essential oil and other compounds. Chaste Tree Vitex agnus-castus. intended to diagnose, treat, cure, or prevent disease. The herb Vitex is also known as Chaste Tree or Chasteberry as it comes from a small shrub that grows in the Mediterranean. turmeric, echinacea, milk thistle, creatine, saw palmetto. This is a female hormone that rises 2 weeks before menstruation. Description. Decreased pain and shorter durations of pain have been demonstrated when chaste tree preparations are used for at least 2 cycles.Carmichael 2008, Mirghafourvand 2016, Roemheld-Hamm 2005, van Die 2009, The widespread use of chaste tree extracts and the relatively safe profile of the preparations make data from animal studies largely irrelevant. There may be benefits that have not yet been proven through research. Scientific Name(s): Vitex agnus-castus L.Common Name(s): Agnus castus, Chaste tree, Chasteberry, Gattilier, Indian spice, Lilac chaste tree, Monk's pepper, Sage tree hemp, Vitex, Wild pepper. Standard Process products labeled as Vegan are devoid of animal-based tissue, animal-based gelatin, or fish oils. Flavonoid content (including kaempferol, quercetagetin, and casticin) has been identified in chaste tree leaves, flowers, and fruits. Chaste tree's berries also can be used for menopausal bleeding irregularities, such as fr… It will survive just fine on rainwater alone, though during long periods of drought, you might like to supplement the tree with occasional watering. Vitex History & Interesting Facts. Chaste tree extract has been used to manage symptoms related to premenstrual syndrome (PMS) and cyclic mastalgia and may be a suitable alternative to standard pharmacological management. Traditionally used in herbal preparations to: Support healthy prolactin and progesterone levels in the body; Encourage healthy menstrual cycling; Ease discomfort associated with premenstrual syndrome; Support normal reproductive function in women* Clerodadienols are potent inhibitors of prolactin release. It is widely used in folk medicine, particularly in South and Southeast Asia. Has a naturally broad and spreading, open, multi-trunk display. Three-months consumption of 15 drops of the commercial product Agnolyt reduced prolactin levels (masking prolactinoma) and returned normal menstruation to an 18-year-old amenorrheic female.Gallagher 2008 However, 20 drops twice daily of a V. agnus-castus compound for 3 months failed to control hyperprolactinemia and related symptoms in a 31-year-old woman with amenorrhea.Tamagno 2007, Experimental studies suggest immunomodulatory effects of chaste tree flavonoids, diterpenes, and other chemical constituents.Ahmad 2010, Chen 2011, Choudhary 2009, Mesaik 2009, The widespread use of chaste tree extracts and the relatively safe profile of the preparations make data from animal studies largely irrelevant. certified organic cane alcohol (71-81%) & distilled water. The vitex species are deciduous shrubs. Select one or more newsletters to continue. This plant does not like to be grown in moist conditions, and in fact, it is one of the few things that the vitex tree will not tolerate. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. small (6 to 7 m) tree or shrub native to river banks in southern Europe and the Mediterranean region Although present in only trace amounts, progesterone, hydroxyprogesterone, testosterone, and androstenedione have been isolated from the leaves and flowers of V. agnus-castus. How We Support Pollinators on Our Organic Farm (& Why It Matters), Support healthy prolactin and progesterone levels in the body, Ease discomfort associated with premenstrual syndrome, Support normal reproductive function in women*. Chaste tree berry has been shown to help balance the progesterone and estrogen levels. Limited evidence exists for its use in amenorrhea, hyperprolactinemia, and menopause. Other Ingredients. Chaste Tree contains high-quality Chaste Tree berries to support healthy female hormone balance. Helps prevent insect bites. This is only a brief summary of general information about this product. Monks have chewed it to decrease sexual desire.Chevallier 1996, Christie 1998, Hobbs 1991. Medically reviewed by Drugs.com. Safe use in children has not been established. These products are not The chaste tree is a native of China, but it has a long history in the U.S. Use in a shrub border, or train for use as a small tree to accent the landscape or patio. Standard Process sells through health care professionals. This … Vitex may influence hormone levels in a number of ways. Chaste Tree Info. V. agnus-castus contains iridoids, flavonoids, diterpenoids, progestins, essential oils, and ketosteroids. Also known as chaste tree or chasteberry, it's often taken as a remedy for women's health problems. Vitex is technically the name for the largest genus in the family Verbenaceae, which comprises 250 species distributed all over the world. * Featured Ingredients: Provides an unusually high dose of the concentrated Chaste tree berry extract For other contraindications and cautions, please refer to the Potential Herb-Drug Interactions Chart. Suggested Use: 1 tablet 1 – 4 tablets daily, or as directed. Available for Android and iOS devices. In vitro studies show that labdane diterpenes have dopamine receptor affinity. Vitex, also known as Chaste Tree or Monk's Pepper, was said to be used as herbal remedy by monks in the Middle Ages to diminish their sex drive, and its common names stem from its use by monks to maintain celibacy. With regard to menopausal symptoms, effects of chemical constituents of chaste tree on dopamine receptors, opioid receptors, and melatonin were described in animal experiments and in vitro studies.Chopin Lucks 2003, Jarry 1994, van Die 2009, Webster 2011, Wuttke 2003, Few controlled clinical trials have evaluated the efficacy of V. agnus-castus as a single agent in the management of menopausal symptoms.van Die 2009 Chaste tree was evaluated in combination with other natural products in the Herbal Alternatives for Menopause Trial. This information relates to an herbal, vitamin, mineral or other dietary supplement. Standard Process products labeled as Vegetarian are considered lacto-ovo vegetarian, which means they are devoid of animal-based tissue, animal-based gelatin, or fish oil. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Numerous mechanisms of action may be involved in inducing apoptosis.Carmichael 2008, Imai 2009, Ohyama 2005, Two case reports provide equivocal results regarding the effectiveness of V. agnus-castus for galactorrhea and prolactinoma. Last updated on Sep 29, 2020. Supplement Description. These fruits have a pepperish aroma and flavor and are collected in autumn.Chevallier 1996, PLANTS 2011, The dried, ripe fruit is used in traditional medicine. Chaste tree berries are used as an herbal treatment for infertility associated with mild corpus luteum insufficiency. © 2020 Standard Process Inc. All rights reserved. Chasteberry, also known as Vitex agnus-castus, is the fruit of the chaste tree, which is native to western Asia and southwestern Europe . It may help normalize estrogen and progesterone. The side effects of chasteberry may include: Acne Headache Menstrual bleeding Rash Stomach upset Weight gain Dizziness Although primarily thought of as one of the most important herbs for regulating female hormones, vitex also has value in the alternative medicine community for treating a … The tree and its berries have the name “chaste” because the fruit was long believed to be an aphrodisiac. The chaste tree is a small (6 to 7 m) tree or shrub native to river banks in southern Europe and the Mediterranean region. The United States National Library of Medicine National Institutes of … However, chaste tree may have estrogenic, progesterogenic, and/or uterine stimulant activity and should be avoided in pregnancy.Brinker 1998, Dugoua 2008, Ernst 2002, Roemheld-Hamm 2005, No consensus exists regarding the efficacy of extracts in increasing milk production.Brown 1994, Roemheld-Hamm 2005 When analyzed chemically, human breast milk revealed no compositional changes after chaste tree use.Taylor 2001 Despite low toxicity and a lack of evidence that chemical constituents pass into the milk, chaste tree products should be avoided during breast-feeding because safety has not been established.Dugoua 2008, Roemheld-Hamm 2005, Case reports are lacking; however, chaste tree has dopamine agonist activity. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Other Ingredients: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, sodium starch glycolate, silicon dioxide, hypromellose and magnesium stearate. Vitex (Vitex agnus-castus) is a plant used in herbal medicine. Limited evidence exists for its use in amenorrhea, hyperprolactinemia, and menopause. An interaction with dopamine agonists (eg, bromocriptine, levodopa), dopamine receptor antagonists, and fertility and contraceptive drugs may be theoretically possible.Taylor 2001, Sliutz 1993, Russell 2002, Daniele 2005, Chaste tree administration is generally regarded as safe for use because it has not been associated with any major adverse reactions. The National Center for Complementary and Alternative Medicine explains that women have used chaste tree berry for thousands of years to treat menstrual problems, infertility and other gynecological issues. This is valuable if it corrects a luteal phase defect, which may contribute to infertility and even miscarriages. Caution: Not to be used during pregnancy and lactation unless otherwise directed by a qualified health care professional. This product may be unsafe when used before surgery or other medical procedures. Enter the chasteberry tree. The plant is cultivated in China. Chaste. Vitex, also known as chaste tree berry, is an herbal supplement which you can use to treat menstrual issues, menopause symptoms, infertility, and a few other conditions. Chaste Tree may also maintain healthy skin in men and women, in circumstances that require a healthy hormone balance. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. Although the Complete German Commission E Monographs supports its use for PMS and cyclic mastalgia, there are limited clinical trials to support these uses. The tree grows well in both temperate and subtropical zones. Chaste Tree Chaste Tree contains high-quality Chaste Tree berries to support healthy female hormone balance. In European herbalism and medicine, vitex extracts are used for uterine fibroid cysts. Information is limited and safety has not been determined in children. Chaste Tree berry has been well studied in clinical trials to support normal hormone levels, particularly progesterone. The fruit and seed are used to make medicine. The effects that this plant can have on the reproductive health of both men and women is largely why it remains in use to this day. Chaste tree extract has been used to manage symptoms related to premenstrual syndrome (PMS) and cyclic mastalgia and may be a suitable alternative to standard pharmacological management. Standard Process products labeled as Gluten-Free have been tested to verify they meet the regulations associated with the United States Food and Drug Administration's gluten-free labeling. Chaste tree (Vitex agnus-castus) is a deciduous shrub that bears clusters of purple flowers in the summer.Left unpruned, it can become a sprawling, vase-shaped shrub that grows to 20 feet tall with an equally wide spread. The safety of the plant's use in children has not been determined.Leung 1996. Background The chasteberry plant, also called chaste tree, is native to the Mediterranean region and Asia. Vitex Agnus-Castus: Which Benefits of Chasteberry Are Backed by Science? The plant has been approved for this condition by the Complete German Commission E Monographs.Blumenthal 2000, In vitro experimental studies suggest dopaminergic activity of the plant's diterpenes, similar to bromocriptine, may result in decreases in serum prolactin. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It blooms in summer, developing light purple flowers and palm-shaped leaves. Monks in medieval Europe ate chasteberries religiously (ha, ha), believing it suppressed sexual desire. This information is not specific medical advice and does not replace information you receive from your health care provider. Improves conditions affecting women’s reproductive systems. Vitex negundo, commonly known as the Vitex, Chinese chaste tree, five-leaved chaste tree, Huang Ping, horseshoe Vitex, is an erect shrub or small tree with quadrangular, densely whitish, tomentose branchlets and smooth, thin, reddish brown bark. It was first cultivated in 1670, and since that time it has become naturalized throughout the Southern part of the country. This information should not be used to decide whether or not to take this product. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Iridoid glycosides have been isolated from the leaves and fruit of the plant and include agnuside and aucubin. *These statements have not been evaluated by the Food and Drug Administration. In Homer's epic The Iliad, the plant was featured as a symbol of chastity, capable of warding off evil. Chaste tree garden care is easy, but there are a few care essentials you need to know to get the most from this outstanding plant. However, chaste tree may have estrogenic, progesterogenic, and/or uterine stimulant activity and should be avoided in pregnancy and while breast-feeding. This plant may also be beneficial in combating breast cancer. MediHerb Chaste Tree encourages a healthy menstrual cycle and eases discomfort associated with premenstrual syndrome. They may contain animal-based ingredients such as dairy, eggs, honey, beeswax, or lanolin. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Vitex agnus-castus … The alkaloid vitricine is present in the plant. Chaste tree has been used to treat menstrual cycle problems and pain, premenstrual syndrome, and menopause. *Percent Daily Values are based on a 2,000 calorie diet. Promote healthy pituitary and hormonal function with chasteberry for horses and dogs. The shrub has long, finger-shaped leaves, blue-violet flowers, and dark purple berries. Historians say that monks chewed chaste tree parts to make it easier to maintain their celibacy. Studies on chasteberry show the herb supports LH production, which in turn boosts progesterone and the luteal phase of the menstrual cycle. Chaste tree berries may help stimulate progesterone. Chaste tree berry, also known as Vitex, is one of the most reliable herbs for young women in their reproductive years, to support a healthy regulated menstrual cycle. Standard Process products labeled as Non-Soy or Non-Soy Formula have been formulated to not contain soy or soy-derived ingredients. Please consult the actual product label for the most accurate product information. Other observational studies and pharmacological experiments suggest V. agnus-castus may be a suitable alternative to standard management, such as hormone replacement therapy, but quality clinical trials are required to support a definitive role in therapy.van Die 2009, Inhibition of testosterone in rats and bone-sparing effects in castrated rats have been demonstrated by extracts of chaste tree.Nasri 2007, Sehmisch 2009, A limited number of high-quality, controlled clinical trials have evaluated the efficacy of V. agnus-castus preparations in treating symptoms associated with PMS (moderate to severe)Atmaca 2003, Berger 2000, He 2009, Ma 2010, Ma 2010, Schellenberg 2001 with most conducted in Germany and China.Freeman 2010 Despite a large placebo response observed in these trials (approximately 50%) and heterogeneity in trial conditions, a 2011 systematic review found that chaste tree extract demonstrated an overall benefit in reducing adverse physical symptoms and poor mood.Dante 2010, Roemheld-Hamm 2005 Several other systematic reviews published between 2014 and 2017 reported similar results usually with administration of 20 to 80 mg/day over 2 to 6 cycles.Izzo, 2016, Jang, 2014, Rafieian-Kopaei 2017, Verkaik 2017 The number needed to treat for improvement in global symptoms score in 1 person was determined to be "4" in a quality controlled trial involving 104 women followed for at least 3 menstrual cycles.Roemheld-Hamm 2005, Schellenberg 2001 Chaste tree has also been favorably compared with fluoxetine in the management of depression associated with PMS.Atmaca 2003 The clinical studies have found the preparations to be well tolerated with few adverse effects, although data from larger controlled trials are still needed.Dante 2010, Freeman 2010, Roemheld-Hamm 2005, The effect of chaste tree extract on hormones in women may be dose-dependent. Some studies suggest lower doses result in increases in prolactin and estrogen as well as decreases in progesterone, while higher doses decrease prolactin levels.Roemheld-Hamm 2005, Daily doses of chaste tree fruit extract are typically 20 to 40 mg, although dosages of up to 1,800 mg/day have been used.Roemheld-Hamm 2005 Chaste tree fruit is available in several different extracts standardized to casticin or agnuside content.Christie 1998, Huddleston 2001, Loch 2000, Information regarding safety and efficacy in pregnancy and lactation is lacking. It was also known to 13th century Europe. The… Although it does seem to occasionally reduce sex drive in women, the effects are less pronounced than the name of this plant suggests. You should talk with your health care provider for complete information about the risks and benefits of using this product. Daily doses of chaste tree fruit extract are typically 20 to 40 mg. Early physicians recognized its effect on the female reproductive system, suggesting its use in controlling hemorrhages and expelling the placenta after birth. The Chastetree berry, or simply Chasteberry (CB) - has a long traditional history of use to help balance hormonal systems. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. Patients who have an allergy to or are hypersensitive to V. agnus-castus or patients who are pregnant or breast-feeding should avoid use. The herb vitex, otherwise known as vitex agnus-castus, chaste tree or chasteberry, is a distant relative of lemon verbena. Vitex may also help keep a variety of insects at bay. Chaste tree berry, or Vitex, comes from a small tree native to the Mediterranean and Central Asia. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. When you see our products labeled as USDA Organic, that means they have been certified as Organic by a USDA-accredited certifying agent. chasteberry for horses. This beautiful garden tree shows large terminal clusters of fragrant lilac-colored blooms, backed by aromatic gray-green foliage. Chaste tree extract helps maintain healthy menstrual cycle duration and flow, as well as reproductive function and breast comfort. Information regarding safety and efficacy in pregnancy and lactation is lacking. Nature’s Way Vitex is a dried powder vitex pill encased in a vegetarian capsule. Vitexlactam A, a labdane diterpene, has been isolated from the fruit of V. agnus-castus. Herbal Secrets Vitex Fruit Chaste Tree Berry Dietary Supplement 400 Milligrams 250 Capsules (Non-GMO) - Supports Women's Health, Mood & Well-Being, Promotes Female Hormonal Balance* 4.3 out of 5 stars 261 $9.99$9.99 ($9.99/Count) Save 5% more with Subscribe & Save Vitex was mentioned many times in the writings of the ancient Greeks and Romans. The name “chasteberry” may reflect the traditional belief that the plant promoted chastity. The fruits of this shrub have been used for some 2000 years as a natural treatment for female fertility and hormonal health. Many studies to date have demonstrated positive clinical outcomes for conditions related to the female menstrual cycle. Flavonoids were isolated from the root bark. It is free from gluten, sugar, salt,… Chaste Tree berry (Vitex agnus-castus) extract 607 mg Country of origin: Albania, Turkey, Croatia. The plant has been recognized since antiquity and has been described in works by Hippocrates (AD 460), Dioscorides (AD 40), and Theophrastus (AD 372). Standard Process products labeled as Non-Dairy or Non-Dairy Formula have been formulated to not contain milk or milk-derived ingredients. Some people also take vitex agnus-castus by mouth for acne, nervousness, dementia, joint conditions, colds, upset stomach, spleen disorders, headaches, migraine, … Research into Vitex is in the early stages, but the results are quite promising. Standard Process products labeled as Non-Grain or Non-Grain Formula have been formulated to not contain any true cereal grain or grain-derived ingredients such as those from wheat, rice, oats, cornmeal, barley, or another cereal grain. Vitex supplements typically contain extracts of the fruit and/or seed of the plant. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Linoleic acid and phytoestrogens (ie, apigenin flavonoid) found in the fruits were identified in other studies as possessing estrogen receptor-specific activity.Rafieian-Kopaei 2017, Ethanol extracts from the fruit of V. agnus-castus have shown in vitro cytotoxic activity against various human cancer cell lines, including cervical, ovarian, breast, and gastric cancer, and small cell lung carcinoma.

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